abstract：:The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Tr...

journal_title：Acta oto-laryngologica

authors： Mohammed el R,Profant M

更新日期：2011-06-01 00:00:00

abstract：CONCLUSION:Chances of hearing preservation are better in patients with vestibular schwannoma (VS) from the superior vestibular nerve (SVN) than from the inferior vestibular nerve (IVN). Pathologic posturography and electronystagmography (ENG) findings are more common in schwannomas from the SVN compared with tumors fro...

journal_title：Acta oto-laryngologica

authors： Borgmann H,Lenarz T,Lenarz M

更新日期：2011-05-01 00:00:00

abstract：CONCLUSION:The Esteem(®) device proved to offer beneficial results in subjects suffering from high frequency, severe bilateral sensorineural hearing loss (SNHL) and may be considered as an alternative procedure to conventional hearing aids (HAs) or electroacoustic stimulation (EAS) systems. OBJECTIVES:Since the Esteem...

journal_title：Acta oto-laryngologica

authors： Barbara M,Biagini M,Monini S

更新日期：2011-04-01 00:00:00

abstract：CONCLUSIONS:A new method for noninvasive standard evaluation of normal endolymphatic space and endolymphatic hydrops using magnetic resonance imaging (MRI) is indicated. OBJECTIVE:To standardize the evaluation of endolymphatic space in the cochlea and the vestibule in healthy volunteers by applying noninvasive intraty...

journal_title：Acta oto-laryngologica

authors： Liu F,Huang W,Wang Z,Chen Q,Liu X,Li S,Wang S

更新日期：2011-03-01 00:00:00

abstract：CONCLUSIONS:Cyclo-oxygenase-2 (COX-2) enzyme would not appear to be constitutively expressed in human perilymph while it is always induced in the perilymph of patients affected by sensorineural hearing loss (SNHL). The COX-2 isoform may be involved in hearing loss and, therefore, pathological states of the inner ear sh...

journal_title：Acta oto-laryngologica

authors： Attanasio G,Viccaro M,Covelli E,De seta E,Minni A,Pizzoli F,Filipo R

更新日期：2011-03-01 00:00:00

abstract：CONCLUSION:No case of death related to surgery in the form of uvulopalatopharyngoplasty, uvulopalatoplasty or nasal surgery for snoring or sleep apnea has been recorded in Sweden among 4876 patients treated between 1997 and 2005. Severe complications of surgery in the peri- and postoperative period, especially in the f...

journal_title：Acta oto-laryngologica

authors： Franklin KA,Haglund B,Axelsson S,Holmlund T,Rehnqvist N,Rosén M

更新日期：2011-03-01 00:00:00

abstract：CONCLUSION:Continuous positive airway pressure (CPAP) therapy improved not only apnea-hypopnea during sleep and sleep structure but also sleep-related deglutition, especially respiratory phase patterns associated with deglutition. OBJECTIVES:Sleep-related deglutition and related respiratory phase patterns in patients ...

journal_title：Acta oto-laryngologica

authors： Sato K,Umeno H,Chitose S,Nakashima T

更新日期：2011-02-01 00:00:00

abstract：CONCLUSION:The degree of contrast enhancement of the cochlea after intratympanic administration of meglumine gadopentetate (Gd-DTPA) or gadodiamide hydrate (Gd-DTPA-BMA) varies widely among patients with inner ear diseases. There was no morphological change in the stria vascularis after Gd-DTPA or Gd-DTPA-BMA was place...

journal_title：Acta oto-laryngologica

authors： Suzuki H,Teranishi M,Naganawa S,Nakata S,Sone M,Nakashima T

更新日期：2011-02-01 00:00:00

abstract：CONCLUSION:The data show that the evaluation of obstruction site in patients with obstructive sleep apnea (OSA) should be performed in the sleep state rather than in wakefulness. OBJECTIVE:The aim of this study was to identify correlation between severity of OSA as measured by the apnea-hypopnea index (AHI) and upper ...

journal_title：Acta oto-laryngologica

authors： Heo JY,Kim JS

更新日期：2011-01-01 00:00:00

abstract：CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...

journal_title：Acta oto-laryngologica

authors： Xiao Z,Yang Z,Liu X,Xie D

更新日期：2011-01-01 00:00:00

abstract：CONCLUSIONS:We conclude that the capsaicin inhalation test is useful to directly assess cough reflex and sensation around the larynx, while it indirectly reflects central nervous system function. OBJECTIVES:To understand the state of the cough reflex before patients with dysphagia start eating. METHODS:We studied the...

journal_title：Acta oto-laryngologica

authors： Imoto Y,Kojima A,Osawa Y,Sunaga H,Fujieda S

更新日期：2011-01-01 00:00:00

abstract：CONCLUSIONS:The microarray analysis identified 39 genes up- or down-regulated by dexamethasone in the cultured tissue of mice cochlea. Of the eight genes most highly affected, several are suggested to have protective effects in the traumatized inner ear (Fkbp5, Glucocorticoid-induced leucine zipper (Gilz), glutathione ...

journal_title：Acta oto-laryngologica

authors： Maeda Y,Fukushima K,Hirai M,Kariya S,Smith RJ,Nishizaki K

更新日期：2010-12-01 00:00:00

abstract：CONCLUSION:Endoscopic cauterization of the sphenopalatine artery and anterior ethmoid artery is a first-line standard of care in managing intractable epistaxis, after the failure of previous packing. Epistaxis occurs in 12% of the population. Treatment is often based on nasal packing that could be poorly effective in t...

journal_title：Acta oto-laryngologica

authors： Minni A,Dragonetti A,Gera R,Barbaro M,Magliulo G,Filipo R

更新日期：2010-09-01 00:00:00

abstract：CONCLUSION:Moxifloxacin was generally well tolerated and highly effective in the treatment of acute bacterial rhinosinusitis (ABS). The incidence of adverse events (AEs) and adverse drug reactions (ADRs) was low. The effectiveness, safety, and tolerability information collected in this study confirm the clinical safety...

journal_title：Acta oto-laryngologica

authors： Zhou B,Jiang X,Zhai L,Xiao S,Wang J,Xiao G,Ruan B,Liang C,Ye Q,Hu B,Wang H

更新日期：2010-09-01 00:00:00

abstract：CONCLUSION:We report a distinct pattern of tongue movement. This is interpreted as a compensatory mechanism after hypopharyngo-laryngectomy with reconstruction using a jejunal autograft. Passage through the oesophagus is mainly passive. OBJECTIVE:Swallowing is normally initiated voluntarily, and afterwards presumed to...

journal_title：Acta oto-laryngologica

authors： Bakkan N,Boysen ME,Line PD,Aasen S

更新日期：2010-09-01 00:00:00

abstract：CONCLUSION:Di-K19Hc is a promising new ototopical antibiotic for treatment of middle ear infections associated with antibiotic-resistant bacteria. OBJECTIVES:Di-K19Hc was previously shown to exert profound antimicrobial activity against a variety of antibiotic-resistant bacteria and fungi. In this study, we evaluated ...

journal_title：Acta oto-laryngologica

authors： Lee YS,Kim YJ,Choi SH,Shin KH,Jang WS,Lee IH,Chung JW

更新日期：2010-08-01 00:00:00

abstract：CONCLUSION:Candidates for hearing preservation cochlear implant (CI) surgery can be divided into: those who benefit from electrical complement (EC) to remaining hearing and don't require additional amplification, those using a combined electric-acoustic stimulation (EAS) and those with the least amount of residual hear...

journal_title：Acta oto-laryngologica

authors： Podskarbi-Fayette R,Pilka A,Skarzynski H

更新日期：2010-08-01 00:00:00

abstract：CONCLUSION:The prognosis of the clinically positive neck in temporal bone squamous cell carcinoma is bad and failures never occur in the neck but at the site of the primary. A clinically positive neck at presentation is a sign of aggressiveness of the primary and, in such cases, therapeutic neck dissection is to be per...

journal_title：Acta oto-laryngologica

authors： Zanoletti E,Danesi G

更新日期：2010-08-01 00:00:00

abstract：CONCLUSION:The external neck brace (ENB) is a new concept in the improvement of peristomal fixation of an automatic stoma valve (ASV), which was evaluated with a new imaging method. The addition of the ENB to the Flexiderm (FLD) and Xtrabase (XB) adhesives significantly reduced absolute mean differences between the spe...

journal_title：Acta oto-laryngologica

authors： Dirven R,Kooijman PG,Maal TJ,Hilgers FJ,Bergé SJ,Marres HA

更新日期：2010-07-01 00:00:00

abstract：CONCLUSION:Our results show a significant difference between skin and cholesteatoma biology in vitro. OBJECTIVES:Cholesteatoma disease is a process of destruction characterized by uncontrolled growth of squamous epithelial cells in the middle ear or temporal bone. The pathophysiology behind the cholesteatoma developme...

journal_title：Acta oto-laryngologica

authors： Helgaland T,Engelen B,Olsnes C,Aarstad HJ,Vassbotn FS

更新日期：2010-07-01 00:00:00

abstract：CONCLUSIONS:The adenovirus-5 vector specifically transduced spiral ganglion cells with high efficiency, suggesting that it is a potential gene therapeutic tool for the survival of spiral ganglion cells with secondary injury. OBJECTIVES:This study aimed to find a suitable viral vector allowing efficient transduction to...

journal_title：Acta oto-laryngologica

authors： Lei L,Han D

更新日期：2010-07-01 00:00:00

abstract：CONCLUSION:Cochlear implantation is a safe procedure in experienced hands, as the rate of severe complications is below 2%. Complications differ between children and adults, and transient disequilibrium/vertigo is the most common complication, followed by wound infection, haematoma/oedema and transient chorda tympani s...

journal_title：Acta oto-laryngologica

authors： Hansen S,Anthonsen K,Stangerup SE,Jensen JH,Thomsen J,Cayé-Thomasen P

更新日期：2010-05-01 00:00:00

abstract：CONCLUSION:Cochlear implantation assessment is possible using commercially available standard flat-detector computed tomography (FD-CT) protocols. Image quality is superior to multislice CT (MSCT). The radiation dose of FD-CT is lower in comparison with MSCT standard protocols and may therefore overcome the limitations...

journal_title：Acta oto-laryngologica

authors： Struffert T,Hertel V,Kyriakou Y,Krause J,Engelhorn T,Schick B,Iro H,Hornung J,Doerfler A

更新日期：2010-04-01 00:00:00

abstract：CONCLUSIONS:The midfacial degloving approach is a favorable option for advanced sinonasal inverted papilloma with a fair recurrence rate, and can replace the lateral rhinotomy approach, which is considered too invasive for benign tumor due to its facial scar. OBJECTIVE:This study aimed to assess the treatment outcomes...

journal_title：Acta oto-laryngologica

authors： Kim WS,Hyun DW,Kim CH,Yoon JH

更新日期：2010-04-01 00:00:00

abstract：CONCLUSION:SOD1 is an important gene related to noise-induced hearing loss (NIHL), and its effect is dependent on noise exposure levels. OBJECTIVES:To test whether the polymorphisms in the CuZn-superoxide dismutase gene (SOD1) are associated with susceptibility to NIHL in the Chinese population. METHODS:Audiometric d...

journal_title：Acta oto-laryngologica

authors： Liu YM,Li XD,Guo X,Liu B,Lin AH,Rao SQ

更新日期：2010-04-01 00:00:00

abstract：CONCLUSION:Changes in the metabolism of arachidonic acid (AA) might be part of a noise-induced compensatory mechanism with regional specificity. OBJECTIVES:The released imbalance of prostaglandins and leukotrienes, both AA metabolites, might result in altered blood flow regulation in the inner ear and probably contrib...

journal_title：Acta oto-laryngologica

authors： Heinrich UR,Selivanova O,Schmidtmann I,Feltens R,Brieger J,Mann WJ

更新日期：2010-03-01 00:00:00

abstract：CONCLUSION:Results from a database for sudden sensorineural hearing loss (SSNHL) demonstrate no correlation between laboratory findings, treatment, and outcome in 400 patients. The patients with pathological test results were not treated differently from those with normal test results. The value of laboratory findings ...

journal_title：Acta oto-laryngologica

authors： Nosrati-Zarenoe R,Hansson M,Hultcrantz E

更新日期：2010-03-01 00:00:00

abstract：CONCLUSIONS:This study confirms a high prevalence of human papillomavirus (HPV)-positive tonsillar tumours (52%). The survival of the HPV-positive group was significantly better in males. OBJECTIVES:We assessed the prevalence of HPV in 137 patients with tonsillar carcinomas, measured the p53- and Ki-67-positive tumour...

journal_title：Acta oto-laryngologica

authors： Hannisdal K,Schjølberg A,De Angelis PM,Boysen M,Clausen OP

更新日期：2010-02-01 00:00:00

abstract：CONCLUSION:The amendments made to pre-existing transcanal approaches limit the possibility of extrusion of the electrode and reduce the time of 'blind' surgery. OBJECTIVE:Alternative techniques to classic mastoidectomy and posterior tympanotomy for cochlear implantation have already been described but their main drawb...

journal_title：Acta oto-laryngologica

authors： Guevara N,Bailleux S,Santini J,Castillo L,Gahide I

更新日期：2010-01-01 00:00:00

abstract：CONCLUSION:The technology of stimulation rates between 1500 and 5000 pulses per second per channel (pps/ch) brings a benefit for all users. However, the fastest possible rate does not necessarily lead to best hearing performance in each individual subject. Individual optimization of stimulation rate is recommended. OB...

journal_title：Acta oto-laryngologica

authors： Buechner A,Frohne-Büchner C,Gaertner L,Stoever T,Battmer RD,Lenarz T

更新日期：2010-01-01 00:00:00

abstract：CONCLUSIONS:Klotho protein content decreases with increasing age, which weakens resistance to oxidative stress, resulting in induced cell death as well as modulating endolymph fluid homeostasis. Down-regulation of klotho also leads to down-regulation of TRPV5 and TRPV6, resulting in modified Ca(2+) homeostasis in the i...

journal_title：Acta oto-laryngologica

authors： Takumida M,Ishibashi T,Hamamoto T,Hirakawa K,Anniko M

更新日期：2009-12-01 00:00:00

abstract：CONCLUSION:Selected patients with Meniere's disease (MD) show an improvement of disability from vertigo after transtympanic ventilation tube insertion, although an effect on vestibular function is not seen if ipsilateral middle ear pressure lower than -50 daPa is used as a selection criterion. OBJECTIVES:Transtympanic...

journal_title：Acta oto-laryngologica

authors： Park JJ,Chen YS,Westhofen M

更新日期：2009-12-01 00:00:00

abstract：CONCLUSION:The narrowing pattern of the upper airway in obstructive sleep apnea patients may be different in sleep as compared with awake. Three different types of obstruction were observed in these subjects during drug-induced sleep. The different obstruction pattern during drug-induced sleep suggests that different s...

journal_title：Acta oto-laryngologica

authors： Chuang LP,Chen NH,Li HY,Lin SW,Chou YT,Wang CJ,Liao YF,Tsai YH

更新日期：2009-12-01 00:00:00

abstract：CONCLUSIONS:This study showed that macrophages, B cells, and T cells occurred at different frequencies, localizations, and times after acute laser tympanic membrane perforation. Immunological cells were most prevalent in the proliferative mass adjacent to the annulus region. The cellular immunological response in fresh...

journal_title：Acta oto-laryngologica

authors： Tahar Aissa J,Hultcrantz M

更新日期：2009-11-01 00:00:00

abstract：CONCLUSION:Chemosensory event-related potentials (CSERPs) were identified in all measurements using the 20 s and the 10 s inter-stimulus interval (ISI) protocol, reducing the recording time to 75% or 57% compared with the standard protocol. A possible explanation for the rising CSERP amplitudes by shortening the ISI in...

journal_title：Acta oto-laryngologica

authors： Kassab A,Schaub F,Vent J,Hüttenbrink KB,Damm M

更新日期：2009-11-01 00:00:00

abstract：CONCLUSION:Extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone but extensive soft tissue involvement did not correlate with prognosis in this study. Resectability of the tumor seems to be major prognostic factor of temporal bone SCC. OBJECTIVE:Prognostic f...

journal_title：Acta oto-laryngologica

authors： Ito M,Hatano M,Yoshizaki T

更新日期：2009-11-01 00:00:00

abstract：CONCLUSIONS:Codeine shows a similar association with profound deafness to other opiates. Good cochlear implant outcomes suggest a sensory disorder. Although macrocytosis could be due to confounding factors, the lack of other consistent findings may signify a vascular pathology. OBJECTIVES:To describe a series of patie...

journal_title：Acta oto-laryngologica

authors： Freeman SR,Bray ME,Amos CS,Gibson WP

更新日期：2009-10-01 00:00:00

abstract：CONCLUSIONS:It has been shown that TRPMs may play a functional role in sensory cell physiology, fluid homeostasis, sensory cell death, and thermosensation in the inner ear, while TRPA1 plays an important role in sensory transduction. OBJECTIVE:To study expression of TRPM1-8 and TRPA1 in the mouse inner ear. MATERIALS...

journal_title：Acta oto-laryngologica

authors： Takumida M,Ishibashi T,Hamamoto T,Hirakawa K,Anniko M

更新日期：2009-10-01 00:00:00

abstract：CONCLUSION:Success and complication rates of endoscopic dacrycystorhinostomy (DCR) creating a window with a drill and without using mucosal flaps are similar to those of external DCR. Moreover, any intranasal or paranasal disease can be treated simultaneously and a superior cosmetic result is achieved. OBJECTIVES:To p...

journal_title：Acta oto-laryngologica

authors： Saratziotis A,Emanuelli E,Gouveris H,Babighian G

更新日期：2009-09-01 00:00:00

abstract：CONCLUSION:Glucocorticoid (GC) administration enhanced apoptotic changes in mature olfactory receptor neurons (ORNs). GC administration may enhance regeneration of olfactory epithelium (OE). OBJECTIVES:The mechanism underlying olfactory epithelial cells turnover involves apoptosis replaced by new ORNs. On regeneration...

journal_title：Acta oto-laryngologica

authors： Takanosawa M,Nishino H,Ohta Y,Ichimura K

更新日期：2009-09-01 00:00:00